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IntensiveBlood-PressureLoweringinPatientswithAcuteCerebralHemorrhageAdnanI.Qureshi,M.D.,YukoY.Palesch,Ph.D.,WilliamG.Barsan,M.D.,DanielF.Hanley,M.D.,ChungY.Hsu,M.D.,ReneeL.Martin,Ph.D.,ClaudiaS.Moy,Ph.D.,RobertSilbergleit,M.D.,ThorstenSteiner,M.D.,JoseI.Suarez,M.D.,KazunoriToyoda,M.D.,Ph.D.,YongjunWang,M.D.,HarukoYamamoto,M.D.,Ph.D.,andByung-WooYoon,M.D.,Ph.D.,fortheATACH-TrialInvestigatorsandtheNeurologicalEmergencyTreatmentTrialsNetwork*ThisarticlewaspublishedonJune8,06,atNEJM.org.DOI:0./NEJMoaABSTRACTBACKGROUND背景Limiteddataareavailabletoguidethechoiceofatargetforthesystolicblood-pressurelevelwhentreatingacutehypertensiveresponseinpatientswithintracerebralhemorrhage.
对于脑出血患者的急性高血压反应，仅有有限的资料指导有关目标收缩压的选择。
METHODS方法Werandomlyassignedeligibleparticipantswithintracerebralhemorrhage(volume,60cm)andaGlasgowComaScale(GCS)scoreof5ormore(onascalefromto5,withlowerscoresindicatingworsecondition)toasystolicblood-pressuretargetof0to9mmHg(intensivetreatment)oratargetof40to79mmHg(standardtreatment)inordertotestthesuperiorityofintensivereductionofsystolicbloodpressuretostandardreduction;intravenousnicardipinetolowerbloodpressurewasadministeredwithin4.5hoursaftersymptomonset.Theprimaryout在线咨询治疗白癜风的医院白癫疯
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